Skin Boosters

Skin boosters treat fine lines and wrinkles by deeply hydrating the skin, enhancing moisture levels, and promoting a plumper appearance. The injections stimulate collagen production, which contributes to improved skin elasticity and reduces the visibility of fine lines. Over time, the combination of hydration and collagen stimulation leads to a smoother and more youthful complexion, addressing the signs of aging.

In 20 subjects treated with small particle hyaluronic acid (SP-HA), the study investigated the effects of SP-HA on skin properties. ^[1] Administered in three treatments on the face, neck, and/or hands, the results showed that SP-HA significantly improved hydration levels in all treated areas, with subjects transitioning from dry to moisturized skin. Moreover, the treatment demonstrated a safe and well-tolerated regimen, positively impacting the skin’s ability to retain moisture, and providing valuable insights into the rejuvenating effects of HA fillers on aging skin.

A study assessed the efficacy and safety of intradermal micropuncture injections using the HA-based gel filler BYRYZN® SKINBOOSTER HA combined with lidocaine (ACROSS Co., Ltd., Gangwon-do, Korea). ^[2] The study included 20 subjects aged between 30 and 60 years, exhibiting signs of skin aging such as wrinkles and loss of elasticity. Following three injections at 2-week intervals, the participants were monitored for 12 weeks. Results showed a significant decrease in the Lemperle wrinkle scale, improved skin parameters, and no serious adverse effects, indicating the safety and effectiveness of multiple microinjections of HA-based gel filler for facial skin aging.

In a multicenter study conducted in Sweden, France, and Brazil, subjects aged 35-50 years underwent full-face aesthetic combination treatments using either abobotulinumtoxinA (ABO) or hyaluronic acid (HA) filler, followed by repeated combined treatment with ABO, HA filler, and Restylane® Skinboosters (RSB). ^[3] Monotherapy involved ≤125 s.U ABO or ≤1 mL HA filler, and at months 6 and 12, both cohorts received ≤125 s.U ABO, ≤2 mL HA filler, and ≤1 mL RSB. The assessment of global facial aesthetic appearance, improvement, first impression, perceived age, wrinkle severity, satisfaction questionnaires, and adverse events revealed that repeated full-face treatment with ABO, HA filler, and RSB yielded superior aesthetic outcomes and higher satisfaction levels compared to monotherapy with ABO or HA filler alone. The study concluded that even modest volumes of HA filler achieved good aesthetic outcomes, and the combination treatments were well-tolerated, resulting in high satisfaction levels and improved aesthetic appearance with each treatment.

Treatment Options

Skin boosters treat fine lines and wrinkles by delivering hydration deep within the skin, stimulating collagen production, and improving overall skin elasticity and texture.

Dehydrated skin lacks sufficient moisture and water content, often leading to a dull and rough complexion. This condition is characterized by the skin’s inability to retain moisture, resulting in tightness, flakiness, and an overall lack of suppleness. Factors such as environmental conditions, inadequate hydration, and the use of harsh skincare products can contribute to the development of dehydrated skin.

Skin boosters are highly effective in treating dehydrated skin by providing deep hydration through the injection of hyaluronic acid, a naturally occurring substance in the skin that attracts and retains moisture. These boosters work to replenish and maintain optimal hydration levels, resulting in improved skin texture, suppleness, and a radiant complexion. The hyaluronic acid in skin boosters also stimulates collagen production, enhancing the skin’s ability to retain moisture and combat dehydration.

In one study, a group of researchers assessed the effectiveness and safety of non cross-linked hyaluronic acid (HA) booster injections for enhancing facial skin quality. ^[4] Twenty individuals, received three injections of non cross-linked HA (1-2 mL) at 3-week intervals. Skin hydration increased significantly at both 1 week and 4 months post-treatment. The booster therapy demonstrated improvements in skin firmness, elasticity, and fatigue, as well as a positive physician’s global assessment, indicating that the procedure is safe and well-tolerated with noticeable benefits in skin quality.

In another study, fifteen female patients with a mean age of 41 years underwent subdermal injections of two non-crosslinked hyaluronic acid (HA) products—one for each hemiface and hemi-neck. ^[5] The procedure, performed with a 25G 50 mm cannula from three entry points, was monitored by ultrasound examinations before and every 6–7 days up to three weeks. The results revealed significant skin quality improvement, as assessed by the Global Aesthetic Improvement Scale (GAIS), with minimal pain, bruising, or edema, making subdermal injections of non-crosslinked HA “skin boosters” a promising option for achieving effective and lasting skin enhancement with minimal trauma.

In a 15-month multi-center study, the efficacy and safety of a hyaluronic acid gel for enhancing aged skin on the dorsal hand were evaluated. ^[6] Adult Chinese subjects with mild or moderate aging received three treatments with hyaluronic acid gel on one hand. The results showed clinically significant improvements in the treated hands, as assessed by the Hand Grading Scale, Global Aesthetic Improvement Scale, and objective measurements of skin elasticity, roughness, and hydration. The hyaluronic acid treatment demonstrated effectiveness in improving skin quality and reducing the signs of aging on the hand, with high satisfaction among subjects.

Skin boosters are effective in treating conditions such as dehydrated skin, fine lines, wrinkles, and overall skin dullness. They can also improve skin texture and elasticity.

While skin boosters primarily focus on hydration and skin quality, they may provide some improvement in the appearance of certain types of acne scars. For more targeted scar treatments, other procedures may be recommended.

The longevity of results can vary but many individuals enjoy the benefits of skin boosters for several months. Maintenance treatments may be recommended to sustain the effects.

Results from skin boosters are often noticeable after the first treatment, with improvements continuing as the skin’s hydration and collagen levels increase.

Discomfort during a skin booster treatment is usually minimal. Many formulations contain lidocaine, a local anesthetic, to enhance comfort during the procedure.

Generally, there is minimal downtime after a skin booster treatment. Some individuals may experience mild redness or swelling but these effects are usually short-lived.

Individuals with dehydrated or dull skin, fine lines, and mild wrinkles are often suitable candidates for skin boosters. A consultation with a skincare professional can determine the best approach for your specific needs.